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    Devro to deliver underlying profits at top end of consensus

    Devro to deliver underlying profits at top end of consensus

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    Market Report: FTSE dips into the red as ‘Blue Monday’ chill begins to bite

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    PowerHouse Energy: ‘Part of solution to two of the greatest environmental challenges of this decade’

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    LXI REIT raises dividend after robust rent collections

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    Tritax Big Box gets upgrade from Peel Hunt after big valuation uplift

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    Castillo Copper considers divestment strategies, including spinning-off prime Broken Hill asset

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    Hillcrest Petroleum closes its C$1.27M non-brokered private placement financing

    Hillcrest Petroleum closes its C$1.27M non-brokered private placement financing

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    Zanaga Iron Ore has one of the most significant undeveloped iron ore projects on the market

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    Devro to deliver underlying profits at top end of consensus

    Devro to deliver underlying profits at top end of consensus

    Market Report: FTSE dips into the red as ‘Blue Monday’ chill begins to bite

    Market Report: FTSE dips into the red as ‘Blue Monday’ chill begins to bite

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    PowerHouse Energy: ‘Part of solution to two of the greatest environmental challenges of this decade’

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    LXI REIT raises dividend after robust rent collections

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    Tritax Big Box gets upgrade from Peel Hunt after big valuation uplift

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    Rio Tinto and Centamin kick off mining theme; Netflix starts FAANG reporting season

    AEX Gold says development of Nalunaq gold project advancing as planned, as it updates on procurement activity

    AEX Gold says development of Nalunaq gold project advancing as planned, as it updates on procurement activity

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    ECR Minerals in middle of hot spot for Australian gold exploration

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    Castillo Copper considers divestment strategies, including spinning-off prime Broken Hill asset

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    Hillcrest Petroleum closes its C$1.27M non-brokered private placement financing

    Hillcrest Petroleum closes its C$1.27M non-brokered private placement financing

    CA Proactive news snapshot: Gevo, Cloud Nine Education Group, Hillcrest Petroleum, Codebase Ventures, Nextleaf Solutions UPDATE…

    CA Proactive news snapshot: Gevo, Cloud Nine Education Group, Hillcrest Petroleum, Codebase Ventures, Nextleaf Solutions UPDATE…

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    Lion One hits high-grade gold in two holes at Fijian project

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    Silvercorp Metals on track to meet fiscal 2021 output guidance as exploration drilling continues

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    Lexaria Bioscience bolsters board of directors with Al Reese Jr

    Hillcrest Petroleum closes its C$1.27M non-brokered private placement financing

    Hillcrest Petroleum closes its C$1.27M non-brokered private placement financing

    Zanaga Iron Ore has one of the most significant undeveloped iron ore projects on the market

    Zanaga Iron Ore has one of the most significant undeveloped iron ore projects on the market

    Thor Mining’s gold assets energise the share price

    Thor Mining’s gold assets energise the share price

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Tiziana Life Sciences upbeat on potential for coronavirus treatment

April 13, 2020
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Tiziana Life Sciences upbeat on potential for coronavirus treatment

  • US and UK listed biotech with three key monoclonal antibody treatments
  • Has applied for a patent for possible coronavirus treatment
  • Other products target liver cancer and autoimmune diseases

 

How it is doing

Shares have soared recently on the potential for Tiziana’s (LON:TILS) TZLS-501 to be useful for people severely ill with coronavirus-related complications.

TZLS-501 is a class of monoclonal antibody (mAb) called an anti-interleukin-6 receptor, or anti-IL6R for short.

On-the-ground testing in China has revealed anti-IL6R mAbs, currently approved for rheumatoid arthritis, has a role to play in treating patients.

So, the country’s National Health Commission has recommended the use of Roche blockbuster, Actemra, for patients infected with COVID-19 with serious lung damage and elevated IL-6 levels.

Other drugs in development 

TZLS-501 is the current focus though last year Tiziana received top-line data from a phase IIa trial of its liver cancer treatment Milciclib as a monotherapy.

A phase 1 trial of its anti-CD3 monoclonal antibody Foralumab delivered via a nasal spray also finished in January with no safety indications and the autoimmune drug being well-tolerated.

Chairman Gabriele Cerrone has high hopes for its nasal delivery method as all autoimmune drugs currently are administered by injection.

 

What the boss says: Gabriele Cerrone, chairman

“The drug [TZLS-501] works not by treating the virus but attacking inflammation in the lungs – it is attacking the two proteins causing this inflammation.

As such, the chances that we will work against another future strain are very high.

“The technology, we think, provides immediate relief thanks to the delivery speed”

Video

Inflexion points

  • Clinical trials get for coronavirus treatments
  • Partner liver cancer and autoimmune drugs
  • Delivery system proves effective for other treatments, opening up huge markets

Published at Thu, 09 Apr 2020 13:30:00 +0000-Tiziana Life Sciences upbeat on potential for coronavirus treatment

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